KEGG   REACTION: R06560
Entry
R06560                      Reaction                               
Name
formononetin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)
Definition
Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyformononetin + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Reaction class
RC00046  C00858_C02920
Enzyme
Pathway
rn00943  Isoflavonoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00942  Pterocarpan biosynthesis, daidzein => medicarpin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.89
     R06560  Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyformononetin + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.90
     R06560  Formononetin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 2'-Hydroxyformononetin + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.90
   R07371  Isoflavone <=> 2'-Hydroxyisoflavone
    R06560  Formononetin <=> 2'-Hydroxyformononetin
Orthology
K13260  isoflavone/4'-methoxyisoflavone 2'-hydroxylase [EC:1.14.14.90 1.14.14.89]
Other DBs
RHEA: 12391

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